Organ distribution is not uniform: Lithium is rapidly taken up by the kidney, but distributed more slowly into the liver, bone muscle or the brain. i hope understand you. This information has not been reviewed or verified by the Agency or any other authority. As published, the average daily lithium intake of a 70 kg adult (American) is between 0.65 and 3.1 mg/day. Upon inhalation, resorption and bioavailability of lithium chloride is expected to be low. A single oral dose of Lithium ion is excreted almost unchanged through the kidneys. Lithium Chloride is a white solid hygroscopic soluble in water, alcohol and ether. The hydrated form can be dried to the anhydrous form by heating with hydrogen chloride gas. If the victim is not breathing, a mouth-to-mouth resuscitation is performed. As counter-ion to sodium, most of chloride is dissolved extracellularly. This substance is also reported as drug to treat bipolar disorder (but rarely used compared to lithium carbonate). Their appearance is shown in figure 2. Lithium is a white hygroscopic solid compound, soluble in water and many other solvents, such as methanol, ethanol, isopropanol, butanol, formic acid, N-Methylformamide, hydrazine, THF, although it is poorly soluble in acetone and ammonia. Only very slight differences were noted, e.g. Lithium chloride affects the nervous system, so it should not be used as a salt substitute. Eye ointment should not be used. In the 1940s, lithium chloride was recommended as a salt substitute for patients with high sodium levels, but this is no longer done because of the risk of lithium poisoning. Lithium chloride cools the air quickly because the chemical contains a huge amount of water for its weight as a solid. Cold water can be used. Based on the high solubility, the systemic availability of chloride from lithium chloride is assumed to be high. National Center for Biotechnology Information. After oral administration lithium chloride is readily and almost completely absorbed from the gastrointestinal tract revealing lithium peak plasma levels after single oral doses peaked at 30-60 minutes (i.e. Lithium chloride is also used as a flame colorant to produce dark red flames. Lithium is not bound to proteins, but is quickly distributed throughout the body water both intra- and extracellularly. Although lithium chloride can be prepared by reacting lithium metal with hydrochloric acid or chlorine gas, this method is both uneconomical and extremely dangerous, as it consumes the expensive metal. Upon contact with the skin, a compound penetrates into the dead stratum and may subse-quently reach the viable epidermis, the dermis and the vascular network. Lithium chloride is a red dye in pyrotechnic displays such as fireworks. Lithium chloride are highly hygroscopic crystals with octahedral geometry similar to that of sodium chloride. Chloride is also distributed throughout the body water, mainly extracellularly and to a low extent intracellularly. If the inhalation is severe, the victim should be evacuated to a safe area as soon as possible. Serum lithium was non-detectable at the first measurement, whereas 0.01-0.05 mM appeared in the blood from the 1st to the 4th day. Thanks 1. Lithium is not metabolised to any appreciable extent in the human body. . for therapy of acute mania and hypomania is 900 to 1800 mg/day lithium carbonate (equivalent to 169 to 338 mg Lithium / day), corresponding to a therapeutic serum concentration of 1.0 to max. LiCl is much better prepared by reacting lithium carbonate with HCl. Lithium may also be absorbed via the lungs.