Human in-vivo trials and cohort and cross-sectional studies, 100 mL (men) or 200 mL (women) organic or conventional Cabernet Sauvignon wine consumed in one sitting; organic samples consumed first; 6-wk washout between exposures, Total antioxidant activity, serum LDL oxidation, total phenol content. This is particularly surprising given the increasing public and policy-level interest in the question of whether there are health benefits from the consumption of organic foods. Second, there are several factors that may have introduced bias in our findings, specifically the exclusion of foreign language publications that did not have an English language abstract and gray literature. However, it is essential that future research (both human and in vitro studies) is better designed and, at the very least, meets the minimum quality criteria applied in this review. It has been suggested that biomarkers may play an important role in measuring disease, but care must be taken in interpretation of such data. The 4 remaining studies used contrasting approaches to test different biological materials in animal or human samples (19–22). In 10 of the included studies (83%), a primary outcome was the change in antioxidant activity (11–14, 17–22). There is increasing global demand for organic food (1), and there is evidence that some consumers purchase organic foodstuffs on the understanding that they are healthier than conventionally produced foodstuffs (2–5). Evidence in this field may be improved if more interdisciplinary approaches to, and funding for, agricultural-health research were supported. These criteria could be criticized for not being sufficiently rigorous because they did not include assessment of factors such as study design, sample size, quality of laboratory methods used, or suitability of statistical analysis. Tuck SL, Winqvist C, Mota F. Land-use intensity and the effects of organic farming on biodiversity: a hierarchical meta-analysis. An independent, expert review panel was created to oversee and advise on the conduct of the review. The most recent systematic literature reviews and meta-analyses have indicated significant and nutritionally-relevant composition differences between organic and conventional foods. Rocz Panstw Zakl Hig. Willer H, Kilcher L. FiBL-IFOAM Report. J Appl Ecol. 2764 infants aged 0–2 y in the KOALA Birth Cohort, Reported habitual diet defined as conventional (<50% organic), moderately organic (50–90%), or strictly organic (>90%), Parent report of infant diet in the second year of life, Parent report of occurrence of eczema and wheezing in all infants; total IgE antibodies and specific IgE concentrations in serum as measures of atopic sensitization in subsample (. First, it is possible that this review did not identify all relevant publications, although we attempted to minimize this possibility by using very broad search terms, repeating our search in multiple relevant scientific publication databases, hand searching reference lists and contacting relevant subject experts. Clinical Practice Variation and Outcomes for Stanford Type A Aortic Dissection Repair Surgery in Maryland: Report from a Statewide Quality Initiative. 2013 Dec 9;8(12):e82429. Dangour AD, Dodhia SK, Hayter A, Allen E, Lock K, Uauy R. Moher D, Liberati A, Tetzlaff J, Altman DG. Taken together, the 12 included articles did not provide evidence of health benefits or harm from consuming organic foods. The review team held 7 progress meetings with the funder of this study. Antioxidant activity (variously defined) was the most commonly reported primary outcome. Cochrane handbook for systematic review of interventions. Conclusion: From a systematic review of the currently available published literature, evidence is lacking for nutrition-related health effects that result from the consumption of organically produced foodstuffs. Organic food is extremely popular and everyone wants to know about its benefits. Eight of the 12 studies (67%) were predicated on the hypothesis that organic production methods result in higher nutrient concentrations in foodstuffs and that these compositional differences would result in different health responses (11, 13, 15, 16, 19–22). USA.gov. HHS The identified articles were very heterogeneous in terms of their study designs and quality, study population or cell line, exposures tested, and health outcomes measured. For full access to this pdf, sign in to an existing account, or purchase an annual subscription. This work was supported by the Sheepdrove Trust. There were several reasons for the exclusion of potentially relevant articles, which included the lack of a study outcome of direct relevance to human public health (n = 22) and the absence of a direct comparison of the health effects of organic compared with conventional foodstuff consumption or exposure (n = 8) (see supplemental material under “Supplemental data” in the online issue). An updated version of the protocol, which was modified on the basis of the experience of conducting an earlier review (8) was finalized on 21 October 2008 and posted online on 30 January 2009. eCollection 2020 Sep 30. This review has several strengths such as its systematic and exhaustive approach, its broad inclusion criteria, and its methodologic rigor. The authors’ responsibilities were as follows—ADD, EA, KL and RU: participated in the design of the study; ADD: managed the study; AA and AH: conducted the literature search and data extraction; and all authors: contributed to the first and subsequent drafts of the article and approved the submitted version. Wang J, Hasanalieva G, Wood L, Anagnostopoulos C, Ampadogiannis G, Bempelou E, Kiousi M, Markellou E, Iversen PO, Seal C, Baranski M, Vigar V, Leifert C, Rempelos L. Food Chem X. 2012;112:309–320. This included higher antioxidant, but lower cadmium and pesticide levels in organic crops, and higher omega-3 fatty acids concentrations in organic meat and dairy products. No association of consumption of organic foods with total IgE antibodies or with IgE-specific measures of atopic sensitization. As far as possible, we adhered to the guidelines for the reporting of systematic reviews (9). Velimirov A, Huber M, Lauridsen C, Rembiałkowska E, Seidele K, Bugel S. Huber M, van de Vijver LP, Parmentier H, et al. This review does not address potential health effects of differences in contaminant content (such as herbicide, pesticide, and fungicide residues) of organically and conventionally produced foodstuffs or of potential wider environmental or occupational health effects of different agricultural practices. Most studies investigated the health effects of specific foodstuffs rather than the diet as a whole, and there was rarely any rationale provided for the quantity and duration of exposure to foodstuffs in clinical trials. 2016 Mar 28;115(6):994-1011. doi: 10.1017/S0007114515005073. Results: From a total of 98,727 articles, we identified 12 relevant studies. Effect of wheat species (Triticum aestivum vs T. spelta), farming system (organic vs conventional) and flour type (wholegrain vs white) on composition of wheat flour - Results of a retail survey in the UK and Germany - 3.